The agricultural hacienda of La Inmaculada Concepción de Palmitos de Arriba is located in the Palmitos Valley, in the present-day state of Durango. It was an important site along the itinerary of the Camino Real de Tierra Adentro, serving as a resting place for travelers heading from the city of Durango to the silver mines of San José de Parral and vice versa.

The hacienda of La Limpia Concepción de Palmitos de Abajo is located in the Palmitos Valley, in the present-day municipality of Rodeo, in the state of Durango. One of the first expeditions to this site was carried out by Juan de Oñate in 1596. Subsequently, the favorable characteristics of the area increased Spanish interest in occupation, as it boasts abundant water resources and fertile land suitable for wheat cultivation and fruit trees.

The Chapel of San Antonio de Padua was built in the 18th century in the former hacienda of San Antonio de Juana Guerra, in the community of Amado Nervo, Nombre de Dios, Durango.

Hacienda de la Zarca, located in the present-day municipality of Hidalgo, was initially one of the first and largest cattle ranches in the state of Durango. This hacienda was an important stop along the itinerary of the Camino Real de Tierra Adentro, serving as a mandatory resting point for travelers journeying from the mines of Parral to Durango or Fresnillo.

Hacienda de San Nicolás de Quijas is located in the state of Zacatecas, in the municipality of Pinos, in the town of Nigromante. The earliest records of it date back to 1651, with Captain José de Quijas Escalante y Saldaña listed as its owner.

The Chapel of Our Lady of Refuge in the former hacienda of San Juan de la Noria, Cuatillos or Pedriceña, is located in the municipality of Cuencamé, Durango. It was built in the 17th century as an agricultural and livestock estate.

The town of Durango was founded on July 8, 1563, by the Basque captain Francisco de Ibarra. It became an important administrative center and the seat of government for the Kingdom of Nueva Vizcaya and the bishopric during the colonial period.

The city of Guanajuato, whose name derives from the Purépecha expression kuanasïuatu: “hill or mountainous place of frogs,” is located in a canyon surrounded by hills. Although this region was inhabited for many centuries by Chichimeca groups, with the arrival of the Spanish and the discovery of various mines, Guanajuato would become one of the richest cities in New Spain during the 17th and 18th centuries.

After the defeat of the Mexica empire, the city of Mexico Tenochtitlan was reconfigured in the Spanish style. The new urban layout would transform Mexico City into a point of significant political, religious, economic, and cultural importance.

In 1529, a group of families belonging to an Otomi population called Nopala, who lived in the province of Jilotepec, set out for the area of La Cañada, in what is now the state of Querétaro. This area was inhabited by Chichimeca groups with whom the native leader of the group, named Conín, maintained a friendship and exchanged animal skins that the locals traded for salt and grains.

The town of San Juan del Río was founded in the first half of the 16th century, as part of the jurisdiction of the mayor's office of Querétaro. It gained importance following the territorial appropriation of the Bajío region by the Spanish, becoming a significant enclave for access to northern New Spain.

After the initial explorations, the Spaniards found in the territory of present-day Zacatecas large expanses of open grasslands with high forage value, crucial for maintaining livestock herds.