The mining settlement of San Pedro de los Chalchihuites was founded on October 15, 1556, by Juan de Tolosa and Martín Pérez de Uranzu. Its prosperity was partly due to nearby hills with springs that provided water for supply and the irrigation of orchards through an acequia system.

The establishment of the mining district Noria de San Pantaleón in 1556 was the result of the work being carried out in the San Martín mines, located in the present-day state of Zacatecas. These mines were important producers of lead, which was required in the region's mines as it was necessary for smelting metals.

In 1555, Juan de Tolosa, along with a group of Spanish adventurers, Franciscan friars, and indigenous people from central Mexico, founded the Real y Minas de Sombrerete in Zacatecas, a region that was previously inhabited by pre-Hispanic groups belonging to the Chalchihuites culture.

The Franciscan order had a prolific presence in various parts of New Spain, particularly in what is now the state of Zacatecas. On January 12, 1707, Fray Antonio Margil de Jesús, along with ten other Franciscans, founded the College of Our Lady of Guadalupe de Propaganda Fide on the outskirts of Zacatecas. This institution interacted with its counterpart in Santa Cruz de Querétaro along the Camino Real de Tierra Adentro. Construction took place between 1713 and 1717, overseen by Father Guardian José Guerra.

The Hacienda of Nuestra Señora de los Dolores de El Carro, formerly known as Hacienda de Espíndola de Ciénaga Grande, was part of the Ciénaga de Mata estate and was located within the jurisdictions of Aguascalientes, Charcas, and Sierra de Pinos.

According to a report by royal officials from Zacatecas in 1731, the town of Noria de Nuestra Señora de los Ángeles was a processing hacienda owned by Bachelor Rodrigo de Guzmán y Ramírez de Prado. Due to the presence of a nearby spring, it enjoyed a degree of prosperity.

Between the 16th and 17th centuries, the Real de Minas de Nuestra Señora de la Concepción de Pinos was a mandatory stop for all those traveling from the mines of Zacatecas to the Consulado de la Nueva España in what is now Mexico City, as well as for those traveling to the towns of San Felipe and San Miguel El Grande.

Hacienda de San Nicolás de Quijas is located in the state of Zacatecas, in the municipality of Pinos, in the town of Nigromante. The earliest records of it date back to 1651, with Captain José de Quijas Escalante y Saldaña listed as its owner.

Finest example of the Chalchihuite Culture. Possibly founded by priests emigrated from Teotihuacan to the plains of Zacatecas, the museum houses a rich collection of finely made instruments, jewellery, figures and offerings, including the symbol of the eagle and the serpent.

One of the most important ceremonial centers of northern Mesoamerica. Its orientation allows for the observation of the Sun’s yearly movement and, like Chichen Itza, it attracts visitors at the time of the spring equinox.