The Mixtec Lord 8 Deer Jaguar Claw ruled over a vast area of the present-day coast of Oaxaca. His memory is preserved in this museum, close to Huatulco. The displays features terracotta figures dating back 2,500 years, pounders for making amate paper, polychrome pottery, green stone objects and much more.

The house where Don Benito Juárez lived when he came to Guelatao, under the tutelage of Antonio Salanueva, and where he started as a servant, progressing to apprentice bookbinder, attorney and eventually governor. The museum brings together documents and personal objects about the great Mexican statesman, telling the story of the Reform War, the French intervention and the triumph of the Republic.

With its adjoining monastery, the church is considered one of the finest Baroque gems of the viceregal period. Both were built by the Dominicans with indigenous labor during the sixteenth and seventeenth centuries. The museum has fine examples of the pre-Hispanic, religious, romantic and contemporary art of Oaxaca. There is also an important ethnobotanical garden, an old library and a newspaper and periodicals library.

During the vice-regal period, Teposcolula was the most important trading area in the Mixteca region. Products arrived here from all parts, such as objects made from gold, cloth and precious stones, while silk textiles were manufactured and cochineal was produced.

Located in the Central Valley of the state of the same name, in pre-Hispanic times it was a Mexica military garrison, while in viceregal times it became one of the most important cities in New Spain. It is distinguished as the birthplace of President Benito Juárez, as well as by its beautiful buildings made of green cantera stone, its cuisine, and its traditional festival, the Guelaguetza.

This was an important trading center both before and after the Conquest. With the construction of the Dominican convent (finished in 1575) it maintained this character as well as being an important center for evangelization. A notable collection of both religious and civic objects from the colonial period.

Its main activity was trade and production of salt. Contemporary with Monte Albán, the Zapotec lineage established here left a historical artistic bequest of magnificent stucco reliefs and artefacts made of bone, as well as mural paintings that can still be seen.

It is believed to have been a fortress for defense against hostile groups, and at the time of the Conquest it was a Mixtec administrative center.

Contemporary with Monte Alban, it is remarkable for the adaptation of the buildings to the terrain, which appear to lean against the hillside. There are also magnificent reliefs depicting ball players.

A Zapotec-Mixtec city still lived in when the Spanish arrived and governed by king Cosijoeza. It is known for its architecture and the tombs discovered here including one with a rich offering of gems and objects made from gold and precious metals.