The mission site highlights Spanish difficulties convincing American Indian populations to adopt Christianity and a sedentary lifestyle--traits that many Europeans considered essential parts of "civilized" life.

Cabeza Creek Crossing was an important link in Spanish and American Indian transportation networks.

The Dimmit County Public Library and Wade House Museum offer books, objects, and events to enrich one's understanding of American Indian groups that inhabited Texas long before the Spanish arrived.

This museum showcases the region's history, culture, industry, and populations through a series of changing exhibits and educational seminars.

Like the Treviño-Uribe Rancho to its south, this museum tells an important story of the Texas-Mexico borderlands in the decade and a half before Texas' annexation by the United States.

The fort is one of the best remaining examples of a nineteenth-century fortified home along El Camino Real de los Tejas (many others were lost during the construction of the Falcon International Reservoir in the mid-twentieth century).

Constructed between 1877 and 1882, the iconic chapel at San Elizario’s former military presidio was the fourth chapel built after the presidio’s establishment in 1788. Soldiers from San Elzeario (also San Elceario), a decommissioned Spanish fort in Guajoquilla, Mexico (present-day Chihuahua), occupied the new presidio to defend area residents and El Camino Real caravans.

Set on a section of El Camino Real de Tierra Adentro locally known as the Mission Trail at the point where the trail moves north from Mexico across the Rio Grande and into the United States, San Elizario remains a well-preserved portrait of more than 300 eventful years of frontier life.

Weathered wooden crosses and marble headstones punctuate the cemetery that fronts the graceful stepped facade of the 1843 Socorro Mission, just south of El Paso, Texas. Highlighting such surnames as Domínguez, Armendariz, Apodaca, Peña, López, Nuñez and Holguin, the cemetery documents over a century of life and death in the 17th-century settlement of Socorro del Sur, located on the southern segment of El Camino Real de Tierra Adentro, locally known as the Mission Trail. The cemetery only tells part of the fascinating survival story of the Socorro Mission of Nuestra Señora de la Purísima Concepción (Our Lady of the Immaculate Conception) and the community it has served for more than 300 years.

The first church at Ysleta was built in 1682 by Spaniards and American Indians who had fled from Isleta (south of present-day Albuquerque, New Mexico) during the Pueblo Revolt. Due to periodic floods of the Rio Grande, the present church was built in 1744, but it was heavily damaged after an 1829 flood and subsequently rebuilt. The last major renovations to the church took place after a 1907 fire partially destroyed the structure.