Monastery founded in 1607 by urbanist Poor Clare nuns; their first residence was in a house opposite the Franciscan friars' orchard, and after twenty-six years they moved to this building. The convent was one of the largest and richest, with an atrium (now the Santa Clara garden), visiting rooms, a profundis room, a refectory, a kitchen, a pantry, an accounting office, work rooms, numerous cells, domestic chapels, an infirmary, an orchard, and other facilities useful to a female monastery. Of the immense convent that covered the current space of three blocks, only the temple, the gatehouse, and the facade of a domestic chapel facing the Guerrero garden remain. After 1864, when the nuns were secularized, the building was divided up and sold to private individuals. Currently, the main cloister is the courtyard of the Federal Judicial Branch, and the rest are residential houses, commercial premises, and a recreational garden.