This room explores daily life in Paquimé. Large display cases contain the essential raw materials used by the community, while smaller side cases highlight various craftspeople and their work:

• Potters, with examples of clay techniques, designs, uses, and functions
• Stoneworkers, who skillfully carved sculptures, ceremonial objects, tools, and utensils
• Shell artisans, creators of decorative and ritual items of great ingenuity
• Copper workers, who produced both large and small objects and jewelry
• Bone artisans, who carved tools from various animal bones
• Weavers and miners, who understood the properties of different minerals and plants
• Carpenters and builders, shown with their construction tools

The room also highlights trade—Paquimé’s main vocation—and the intricate networks connecting the Gran Chichimeca and Mesoamerica.

In the second corridor, niches contain offerings to the gods—finely crafted objects in stone, ceramics, and metal used by shamans, priests, and spiritual healers. Musical instruments on display suggest both ceremonial and recreational uses. Opposite the niches, a section presents a depiction of the city's decline and abandonment, likely in the 13th century. Whether caused by war, prolonged drought, or a combination of factors, the people of Paquimé set off “toward other lands.” A map illustrates post-Paquimé settlements, with emphasis on the site of Tres Ríos.