The "portería" served as the threshold to the Colegio de Guadalupe and was likely built after 1775, when the cloisters of the Passion of Christ and of Saint Francis were completed. It was customary at the time to add the portico as the complex expanded. This space was overseen by the porter father, who played a key role as the eyes and ears of the guardian.

The porter kept track of friars who left the college and laypeople who occasionally entered, and he also reported on missionaries who, for various reasons, needed to stay overnight.

In this room stands the frontal of a Neoclassical altar. Recent research suggests that during the Reform era (1856–1859), the college was partially divided, with one section remaining under Franciscan care. During that time, this room may have functioned as a small chapel reserved for the friars. In 1878, the Franciscans ceded the porter's lodge, the upper and lower cloisters, and the choir to the government of Zacatecas. The topographic survey for this division was carried out by surveyor Sixto Espinoza.

Here you can also find portraits of the founders of the Colegio de Guadalupe: Friars José Guerra, Antonio Margil, and Pedro de la Concepción y Urtiaga.